Marrowpan is a complete ready-to-use medium intended for in vitro diagnostic procedures with a short term culture of bone marrow and other hematopoietic cells for cytogenetic studies. Marrowpan is intended for in vitro use and has been designed for establishing cultures of bone marrow and leukemic blood cells, which then can be used in karyotyping, fluorescence in-situ hybridisation (FISH) or other cytogenetic procedures. Marrowpan can be used as a neutral medium to culture different haematopoietic cells (myeloid and lymphoid lineages) present in bone marrow or leukemic blood samples. Marrowpan is also used together with a mitogen specific for B or T lymphocytes where these particular lineages are being investigated.
Marrowpan is supplied frozen as a complete medium, ready- to-use in a 100 ml format. It is based on alpha-MEM and contains antibiotics, L-glutamine, fetal bovine serum (FBS), hormones and growth factors.
Marrowpan is a complete medium (ready-to-use) for the cultivation of cells from peripheral blood or bone marrow. It is suitable for a rapid expansion of blood cells in order to investigate leukemic diseases (e.g. ALL, AML, CLL, CML, MPN, MDS). The number and quality of metaphases in Marrowpan are significantly higher and independent of individual batches as compared to serum-containing media.